If you’re having trouble scanning with your Mac - it’s not just you, and Apple’s apparently on it. iMore says Apple is working on a fix for Mac users who suddenly don't have permission to use their scanner.
The problem - put simply - is that some people can’t scan. Put less simply, the piece has Apple saying:
When attempting to connect to your scanner and begin a scan, you might get a message that you do not have permission to open the application, followed by the name of your scanner driver. The message says to contact your computer or network administrator for assistance, or indicates that your Mac failed to open a connection to the device (-21345).
While the while the Mac-wielding world waits for a legit fix, Apple does have steps one can follow for a workaround:
Quit any apps that are open.
From the menu bar in the Finder, choose Go > Go to Folder.
Type /Library/Image Capture/Devices, then press Return.
In the window that opens, double-click the app named in the error message. It's the name of your scanner driver. Nothing should happen when you open it.
Close the window and open the app you were using to scan. A new scan should proceed normally. If you later choose to scan from a different app and get the same error, repeat these steps.
No word on when a less cumbersome fix will be out, according to iMore.